Substance Use Disorders

Substance Use Disorders

The Medpace Difference for Substance Use Disorder Studies

  • In-house psychiatrist, neurologists, imaging specialists, and operational teams with experience in managing and executing substance use disorder studies
  • Wholly-owned imaging core lab with an end-to-end suite of global imaging services ensuring imaging components are seamlessly integrated into the complex structure of the overall trial
  • Global central lab with safety and biomarker analysis to support substance use disorder studies
  • Cardiovascular Core Lab can fully quantify the cardiovascular effects in the treatment of patients with substance use disorders
  • Multi-dimensional recruitment model that enables us to implement customized recruitment and retention strategies that identify, recruit, and retain challenging patient populations associated with substance use disorders

Specialized Imaging for Neuroscience Clinical Research

Neuroimaging has played a key role to clarify that substance-use disorders are associated with changes in brain structure, function and neurochemistry. Brain imaging studies have provided information on drugs, neurobiological effects, helped explain the causes and mechanisms of vulnerability to drug abuse, and yielded important insights into abusers’ subjective experiences and behaviors, including their struggles in recovery.

The five primary brain imaging techniques used to reveal different structures of brain or functions of brain are:

  • Structural Magnetic Resonance Imaging (MRI)
  • Functional MRI
  • Magnetic Resonance Spectroscopy (MRS)
  • Positron Emission Tomography (PET)
  • Single Photon Emission Computed Tomography (SPECT)

Medpace Imaging Core Lab provides an end-to-end suite of imaging services, including consultation on imaging biomarker strategies, image acquisition protocols, image collection/archiving services, and image analysis across imaging modalities and therapeutic areas.