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Medpace Bioanalytical Laboratories

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Early Phase Clinical Development

Early Phase Clinical Development sets the course for a long and trusted relationship. Learn more about the benefits and capabilities of Medpace Clinical Pharmacology Unit and Medpace Bioanalytical Laboratories.

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The Medpace Bioanalytical Laboratories provide bioanalytical services in all stages of drug development – from discovery to post-marketing. If you have any questions or need more information, please contact us.

Led by an executive management team that averages more than 20 years of pharmaceutical and bioanalytical study experience, we are focused on providing accurate, high-quality results in a timely, secure, and cost-effective manner. Our bioanalytical laboratory experts work in collaboration with the medical and regulatory experts at Medpace to partner with your team to transfer and validate methods and ensure fast turnaround of analyses.

Leveraging state-of-the-art instrumentation, techniques, and facilities, our team of experts has experience in a broad range of analytical support. Working in a good laboratory practice (GLP) compliant setting, the Medpace Bioanalytical Laboratories provide method transfer, development, validation, and analysis of preclinical and clinical biological samples. We have extensive expertise in developing sensitive methods for LC-MS/MS – qualifying multi-analysis, metabolites, prodrugs, and light- and temperature-sensitive compounds – and we routinely establish and validate analytical methods for mouse, rat, rabbit, dog, monkey, and human species. Our discovery team regularly performs fast PK, bioavailability, and early toxicology studies.

Areas of bioanalytical expertise include:

  • Advanced mass spectrometry technologies for bioanalytical analysis
  • All bioanalytical aspects for small and large drug molecules according to GLP, OECD, and ICH compliances
  • Rapid transition of methods between species and matrices while providing performance according to FDA, OECD, and ICH guidelines

We apply the following bioanalytical services from drug discovery throughout drug development:

  • Dose escalating studies, with analysis and reporting capabilities for thousands of samples within short timeframes
  • Method development, feasibility, and validation
  • Nonclinical toxicokinetic (TK) studies
  • Pharmacokinetic (PK) screening
  • Clinical PK/bioavailability studies
  • Bioequivalency studies
  • Bioavailability studies
  • Drug discovery
  • Drug-drug interaction studies
  • Pre-clinical and clinical sample analysis
  • Clinical study-compliance samples

Medpace Bioanalytical Laboratories provide complete services for labeling, shipping, and storing biological samples. Our facility features:

  • Refrigerated storage (4ºC)
  • Low temperature storage (-20ºC, -70ºC, and -80ºC)
  • Emergency back-up electrical and heating services
  • Video security
  • Onsite archive facility
  • Bar coding system

Our state-of-the-art equipment, instrumentation, and software includes:

  • AB Sciex 6500 high resolution Q Trap LC-MS/MS systems
  • AB Sciex 5600 high resolution LC-MS/MS systems
  • API-5500 Sciex Q trap LC-MS / MS Systems
  • API-4000 Sciex LC-MS / MS Systems
  • UFLC Shimadzu LFLC/HPLC LC-30XR Systems (19,000 PSI)
  • HPLC Shimadzu UFLC / LC-20 Systems
  • ELISA instruments with Absorbance, Fluorescence, Luminescence
  • MSD Sector Imager 2400 (Multiplex)
  • Eppendorf qPCR (Realplex)
  • GC-MS
  • Watson LIMS System vs7.3
  • Automated sample preparation and TomTech Quadra SPE 4
  • Complete services for labeling, shipping, and storing biological samples

See a list of our currently available methods.

Want to learn more? Watch our video, or contact us.