Neurology Imaging
Medpace is the Core Lab of Choice for Neuroimaging
Medpace is the Core Lab of Choice for Neuroimaging
Why Sponsors Partner with Medpace Core Labs for Neuroimaging
Medpace Core Labs (MCL) delivers comprehensive neurology imaging solutions designed to enhance and expedite biopharmaceutical and medical device development. Our team is equipped to support clinical trials with advanced neuroimaging techniques and rigorous quality control processes. Medpace ensures efficient management and execution of neuroimaging trials through a centralized process, maintaining high standards of quality assurance and compliance. They provide insights and support across a range of neurological conditions, ensuring that trials are conducted with precision and expert oversight.
Medical, Scientific, and Technical Expertise in Neuroimaging for Clinical Trials
MCL’s neuroimaging program is supported by an integrated team comprised of scientists, clinicians, technologists, project managers, and coordinators. Our team of experienced professionals brings training and board certification in MRI, CT, SPECT/PET, and Ultrasound, to clinical trials using neuroimaging biomarkers within their clinical endpoints. Our imaging project managers have decades of experience in managing teams and processes for all aspects of neurodevelopmental, neurodegenerative, and neuromuscular disorder trials, including site qualification, image acquisition, reading, analysis, quality checks, data management, and documentation.
Team members include:
- Clinicians: Board-certified radiologists and neurologists with extensive clinical trial experience
- Scientists: Medical Physicists, Physicists, and Engineers with PhD and MS level training covering all neuroimaging modalities and analysis methods
- Imaging Technologists: Clinically trained and certified with clinical trial experience across modalities
- Project Managers: Specialized training and skills for managing neurodevelopmental, neurodegenerative, and neuromuscular disorder trials
- Project Coordinators: Experienced in Medpace processes for clinical trial operations, documentation, and quality assurance
Neurology Imaging Experience
MCL delivers expert neuroimaging solutions for clinical trials, supported by an experienced team and cutting-edge technology.
Experience
- Neuro-oncology
- Neurodegenerative Disorders
- Parkinson’s Disease
- Huntington’s Disease
- Alzheimer’s Disease
- Multiple Sclerosis
- Neurodevelopmental disorders
- Pediatric rare diseases
- Metabolic disorders
- Ataxias
- Bipolar Disorder, Schizophrenia, & Mental Health
Modalities
- X-Ray
- Computed Tomography (CT)
- Single-Photon Emission Computed Tomography (SPECT)
- Positron Emission Tomography (PET)
- Magnetic Resonance Imaging (MRI)
- Magnetic Resonance Spectroscopy (MRS)
Advanced Neuro-MRI Methods
- DTI – Diffusion Tensor Imaging
- NODDI – Neurite orientation dispersion and density imaging
- fMRI – functional MRI
- fcMRI – functional connectivity of resting state fMRI
- PET – Positron Emmision Tomography with targeted tracers
- Structure MRI with quantitative volumetric segmentation
- WM/GM
- Cortical Thickness
- ASL – Arterial Spin Labeling for quantitative perfusion imaging
- SWI – Susceptibility weighted imaging
Streamlined Processes
- Centralized processes for the management and execution of neuroimaging trials with global and local sites
- 24/7 global site management
- Imaging Review Charter (IRC) and other documentation
- Rigorous quality control and validation process
- Compliant with Metrics Champion Consortium (MCC)
Expert Quality
- Standard operating procedure (SOP) driven processes
- CFR Part 11 compliant vendor-neutral imaging systems for clinical trials
- Dedicated imaging quality assurance (QA) officers and processes
- Validated customized image analysis tools
- Qualified sites, qualified readers, professional management
