Accelerating Complex Respiratory Clinical Trials with Specialized Expertise
According to the Global Burden of Disease Study 2019, over 450 million patients suffer from chronic respiratory diseases globally, with asthma representing the highest prevalence. Moreover, around 4 million deaths were caused by respiratory conditions such as COPD and lung cancers. Both mortality and prevalence of chronic respiratory diseases have increased significantly over the past three decades, underscoring the urgent need for safe and effective therapeutic measures.
Despite this substantial unmet need, the pace of innovation in respiratory drug development has lagged, driven by complex trial designs and longer durations. Medpace is built to address these challenges. As a full-service Clinical Research Organization (CRO), we combine deep therapeutic expertise with operational excellence to streamline respiratory clinical development.
Accelerate your path to approval with guidance from our integrated team of medical, operational, and regulatory experts. Our extensive experience and consistent track record in respiratory studies enable us to adapt to the unique requirements of each program, proactively manage complexity, and help you maximize your trial budget.
Making the Complex Seamless® in Global Respiratory Trials
Drive the successful execution of respiratory/pulmonary clinical trials with a partner that combines strong communication, early strategic planning, and extensive experience collaborating with global regulatory authorities. For over 30 years, Sponsors across emerging biotechnology and global pharmaceutical companies have trusted Medpace to lead their clinical development programs.
Gain a competitive advantage by leveraging our global expertise and experience, with benefits that include:
Comprehensive support via our dedicated global regulatory submissions and global regulatory affairs teams
ClinTrak®, Medpace’s proprietary clinical trial management system, provides aggregate data and reporting to support all aspects of a project to enhance and streamline study management
Extensive experience across a wide range of indications, including but not limited to:
Asthma
Acute Respiratory Distress Syndrome (ARDS)
Alpha-1 Antitrypsin Deficiency (AATD)
Bronchiectasis
Chronic Obstructive Pulmonary Disease (COPD)
Cystic fibrosis
Emphysema
Idiopathic Pulmonary Fibrosis (IPF)
Interstitial Lung Disease
Lung Cancer
Mesothelioma
Obstructive Sleep Apnea
Bacterial and Viral Pneumonia
Pulmonary Embolism
Pulmonary Hypertension
Sarcoidosis
Strategic Approach to Recruitment & Retention
Medpace applies a multi-dimensional recruitment model to design and execute customized strategies for challenging patient populations. Our dedicated, in-house patient recruitment and retention team brings deep experience in recruiting respiratory patient populations, providing strategic guidance to accelerate patient enrollment. Through a patient-centric approach that minimizes burden while enhancing participant experience, we drive successful outcomes in study design, adherence, satisfaction, and data quality.
Strong, Long-Term Relationships
Our established relationships with global thought leaders, high-performing investigative sites, site networks, and patient advocacy organizations further strengthen recruitment and retention. This network helps facilitate strategic site selection, efficient start-up, targeted recruitment, and implementation of proven retention strategies—ensuring timely, high-quality enrollment that is key to the success of respiratory programs.
Respiratory Clinical Trial Experts
In-house, pulmonologists, clinical immunologists, and allergists add an additional layer of medical and scientific expertise and are embedded within the project team throughout the lifecycle of your trial. They provide leadership, consulting with Sponsors, along with training project teams and investigative sites to ensure our operational strategy is firmly aligned with your scientific and medical objectives. Additionally, our operational teams, including clinical trial managers and program coordinators, are therapeutically aligned to provide specialized training to sites and help mitigate challenges.
Alpha-1 Antitrypsin Deficiency (AATD) Consortium of Experts
The Medpace AATD Consortium brings together leading medical, operational, and regulatory experts from around the world who are dedicated to advancing AATD clinical development. The cross-functional team meets regularly to share lessons learned, apply best practices, and develop innovative solutions tailored to the unique challenges of AATD. With a shared commitment to accelerating progress, the consortium focuses on seamless execution of global AATD trials through collaboration and innovation.
Key focus areas include:
Analyzing the evolving competitive landscape to optimize country selection and enrollment
Developing and refining global patient recruitment strategies
Creating project management tools to accelerate startup and reduce operational hurdles
Sharing site-specific insights from KOLs to minimize duplication of efforts
Supporting ongoing education and training of new members
“Together we can make the world breathe easy. Delighted to work among scientifically driven individuals who work together towards the development of novel therapeutics and routes of drug delivery.”
