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Central Laboratories

State of the Art Flow Cytometry Techniques Now Supported in Singapore

  • September 17, 2018
Flow cytometry is well established as a research tool in clinical research. This is due to its wide range of cellular parameters that can be measured with fluorescent reagents and its ability to measure as many as 10 of these parameters simultaneously. This whitepaper discusses flow cytometry and how it lends itself as a useful clinical trial tool in a wide variety of therapeutic areas. You can access that whitepaper in its entirety here.

Flow Cytometry Capabilities

Medpace offers global flow cytometry capabilities, with flow cytometry departments located at our US, Belgium and Singapore central laboratories. Medpace has an experienced flow cytometry team overseen by PhD-level scientists with over 40 years of experience designing, analyzing, and interpreting multicolor flow cytometry assays. Whether a custom panel needs to be developed or a method needs to be transferred to our laboratory to support a global clinical trial, we have the experience to quickly validate and implement the flow cytometry testing. Flow Cytometry

Flow Cytometry Services include:

  • Sample Types
    • Whole blood
    • Peripheral Blood Mononuclear Cells (fresh or cryopreserved)
    • Bone Marrow Aspirate
    • Cerebral Spinal Fluid
    • Available soon: Dissociated tumors/tissues
  • Analysis
    • Real time
    • Batch analysis
    • FlowJo, FACSuite, SpectroFlo
  • Validation
    • Global data harmonization
    • CLSI H62 guidelines
    • Quality Assurance review
    • IVD or RUO assays
  • Custom Panels
    • Receptor occupancy assays
    • Immune cell phenotyping and Immune cell function assays
    • CAR T-cell assays (PK and PD)
    • Intracellular cytokine assays
    • Functional assays
  • Ready-To-Go Panels
    • TBNK (Whole blood)
    • PNH (Whole blood)
    • CD34+ stem cell count (Whole blood)
    • T Cell exhaustion (Frozen PBMCs)
    • CD4/CD8 (Frozen PBMCs)
    • NK (Frozen PBMCs)
    • DC panel (Frozen PBMCs)
    • Monocytes panel (Frozen PBMCs)
    • B Cell panel (Whole blood)
    • Intracellular cytokines panel (Fresh PBMCs)
    • T, B, NK, NKT, Monocytes, DC, ILCs and Basophils (26 Colors on PBMCs)
Medpace also has strategic lab partnerships who have extensive experience performing flow cytometry hematomalignancies, LAIP (leukemia-associated immunophenotypes), and MRD (minimal residual disease) analysis requiring a pathologist review and interpretation. To learn more about Medpace’s central laboratories and how we can benefit your next clinical trial, contact us here.