LDL particle binding to the LDL receptor

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Direct Measurement of Lp(a)-Cholesterol Improves LDL-C Accuracy in Patients with Elevated Lp(a)
Direct Measurement of Lp(a)-Cholesterol Improves LDL-C Accuracy in Patients with Elevated Lp(a)

Successfully Executing Biomarker Strategies

Medpace’s central laboratories offers a unique advantage for Sponsors seeking advanced lipid biomarker analysis through its exclusive research rights from Megaron, Inc. for direct Lp(a)-cholesterol measurement. This assay is derived from and validated against the original gold-standard methods developed in Dr. Sotirios Tsimikas’ laboratory, ensuring scientific rigor and reliability. As the only reference lab to offer both Lp(a)-C and corrected LDL-Ccorr testing, Medpace also provides optional panels including Lp(a), apoB, OxPL-apoB, OxPL-apo(a), and inflammatory markers for comprehensive lipid and cardiovascular risk profiling. Developed in collaboration with leading experts in Lp(a) and lipoprotein biology, including Dr. Santica Marcovina and Dr. Tsimikas, these assays are fully suited for both GCP-aligned clinical trials and observational research.

Whitepaper: Direct Measurement of Lp(a)-Cholesterol Improves LDL-C Accuracy in Patients with Elevated Lp(a)
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Scientist working in the laboratory

Global Labs – Fully Integrated for Efficiency 

Since most clinical trial requires laboratory support, having wholly-owned entities with a broad range of capabilities and comprehensive test menus  provides built-in efficiencies and collaboration. In concert with the Medpace CRO or working on standalone projects, experts from our central laboratories and bioanalytical laboratory  can help plan and execute your testing needs.