Neurodegenerative Disease CRO

Design and conduct successful neurodegenerative disease studies with guidance from our cross-functional team of neuroscience experts

Design and conduct successful neurodegenerative disease studies with guidance from our cross-functional team of neuroscience experts

A computer with brain scans

Making the Complex Seamless® in Neurodegenerative Clinical Development

Adequately addressing the increased complexity of neurodegenerative disease drug development requires active engagement and a high level of expertise. Accelerate the execution of your neurodegenerative disease study by partnering with a global clinical research organization (CRO) that understands the challenges of neurodegenerative diseases and has the necessary experience and expertise to help you overcome them. As a scientifically-driven CRO with a dedicated team of neuroscience experts, Medpace has the scientific leadership, operational execution, and comprehensive services to help accelerate your neurodegenerative disease compound to approval.

The Medpace Advantage

Gain a competitive advantage for your program by leveraging our global footprint, strategic medical, regulatory, and operational leadership, and support from our fully integrated central labs and core imaging services to enhance and expedite development.

Why Choose Medpace for Neurodegenerative Disease Studies?

Partner with a global CRO with a cross-functional collaborative model to set your Neurodegenerative trial up for success. The Medpace Neuroscience Team can support your clinical trials through:

  • Vast experience successfully managing studies in rare disease indications provides the knowledge and resources to ensure success in genetic marker focused studies that must recruit and retain the hardest to find patients
  • In-depth knowledge of screening tools and rating scales and experience providing oversight for rater services including subjective assessments, interrater reliability, and scale validation
  • Flexible, highly-customizable ePRO solutions that are fully integrated into our proprietary data management system, ClinTrak
Neuron Cell Network Medical Background

medical doctor seeing Magnetic Resonance Imaging (MRI) film

Central Laboratory Capabilities

With strategically located central laboratories in the US, Europe, China, and Singapore, Medpace has the global reach and safety and biomarker analysis capabilities to conduct neurodegenerative disease studies in concert with our full-service CRO or as a standalone service. Key highlights include:

  • Extensive menu of biomarkers that use state of the art techniques, and provide results that enable patient stratification and improve prediction of drug efficacy and safety
  • Scientific engagement throughout the development lifecycle from our global team of experts who have extensive central laboratory operations experience
  • In-house logistical team that manages all shipments of collection kit supplies and laboratory manuals to clinical sites
  • Seamless integration with a robust network of laboratory partners, providing specialized neuroscience testing such as CSF biomarkers and genotyping

Specialized Imaging for Neurodegenerative Disease Clinical Research

High-quality image acquisition and interpretation is crucial for the success of neurodegenerative disease trials. Medpace Core Labs provides comprehensive central imaging services to support imaging endpoints for neurodegenerative disease trials using fully regulatory-compliant platforms. Our fully-integrated, wholly-owned imaging core lab ensures imaging components are seamlessly integrated into the complex structure of the overall trial. Key services include:

  • Site assessment, qualification and training, imaging protocol optimization and standardization
  • Centralized blinded assessments, including patient eligibility and safety reviews
  • Advanced data processing, e.g. global and regional brain volume and atrophy quantification with MRI
  • Support of multiple modalities: MRI, PET, fMRI
Medical Hospital: Neurologist and Neurosurgeon Talk, Use Computer, Analyse Patient MRI Scan, Diagnose Brain. Health Clinic Lab: Two Professional Physicians Look at Functoning CT Scan Find Treatment

Neurodegenerative Disease Experts

Our global team of experienced medical, clinical, and regulatory experts have been involved in the management and execution of neuroscience trials around the world. In-house neurologists with deep backgrounds in conducting complex neuroscience studies are embedded into your program from project initiation to completion, providing hands-on leadership and translating medical knowledge into execution.

Key Neurodegenerative Disease Indications

Our physicians and staff have experience leading clinical trials in neurodegenerative diseases including:

  • Alexander Disease
  • Alzheimer’s Disease
  • Frontotemporal Dementia
  • Motor neuron disease | Amyotrophic Lateral Sclerosis
  • Friedreich’s ataxia
  • Huntington’s Disease
  • Memory Loss | Mild Cognitive Impairment
  • Multiple System Atrophy
  • Neuronal Ceroid Lipofuscinosis
  • Parkinson’s Disease
  • Spinocerebellar Ataxia

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